Magnetic bead-based purification has become the preferred method for isolating DNA, RNA, and other target molecules from various biological sample types. The quality and quantity of the extracted molecules can be significantly higher than other methods, such as spin columns, while the cost per sample can be lower. The IsoPure™ Mini from Accuris Instruments is a compact, automated purification system that improves efficiency and reproducibility using the magnetic bead-based method. Capable of processing up to 16 samples at one time, the instrument is easy to set up, program, and operate. Mixing, magnetic bead transfer, washing, and elution steps are performed automatically, saving valuable hands-on time. The purification process can be completed within 10 to 60 minutes, depending on the reagent kit used and the complexity of the program.

• Fast, reliable, and reproducible results
• Compatible with all popular magnetic bead kits
• Compact (8x10 inch footprint)
• Process up to 16 samples
• Programmable with PC software or Android App
• Sample volume 50 µL - 1000 µL

Programming via Android™ App or PC Software

Creating a protocol is simple using the IsoPure app or PC software, both included on a USB flash drive with each instrument. Mixing speed, sample temperature, and magnetization parameters can all be programmed. When using the IsoPure app on an Android device, the saved protocols can be transferred to the instrument via Bluetooth or using the included barcode scanner. The PC software allows programming and transferring via USB flash drive or barcode scanner. Free lifetime app updates provide access to newly available features.

QR Code Scanning System

A handheld scanner is included with each IsoPure™ Mini, providing a convenient and fast method for loading protocols onto the instrument. After creating or opening a protocol on an Android device or a connected PC, a QR code can be generated. Simply scan the QR code to instantly transfer the protocol. QR codes are also available in kit instruction manuals for instant loading of optimized programs.

Protocol Optimization

Accuris Instruments has partnered with leading magnetic bead kit manufacturers to develop and optimize protocols for specific applications. To request scripts for specific kits or assistance in optimization, contact the IsoPure™ Technical Support Team at info@accuris-usa.com.

Sample Temperature Control

Heating sample mixtures during the lysis and elution steps can significantly improve results. Heating strips on the sample platform can be precisely set to any temperature between ambient +5°C to 120°C. Both deep well plates and 6-well reagent vessels fit into the contoured heating strips for efficient heat transfer. Two cooling fans maintain ambient temperature inside the housing and heating strips.

Connection Ports

The IsoPure™ Mini can store up to 100 protocol files in internal memory, which can be transferred between instruments or to a computer for storage or sharing. Simply insert the included flash drive to export selected files. Internal protocol management can be performed via the instrument's touch screen or using the included mouse.

UV Sterilization

An ultraviolet sterilization lamp (UVC) inside the processing chamber eliminates most bacterial, viral, and stray genomic DNA contaminants. This safeguard reduces the possibility of contamination and unwanted target amplification in downstream applications.

Touch-Screen Control Panel

The control panel on top of the IsoPure™ Mini allows quick selection of stored protocols and instrument control. To execute a protocol, select it from the file list, insert a prepared sample plate (or 6-well reagent vessel) and tip combs, and press the start button. Run parameters and operating status are displayed during sample processing.

IsoPure™ Consumables

Accuris offers magnetic tip combs, deep well plates, and 6-well sample strips designed to fit the IsoPure™ Mini. Produced using virgin polypropylene and packaged in a sterile environment, these consumables are guaranteed to be contaminant-free. The 8-place magnetic tip combs lock into position inside the instrument's processing chamber.

There are two options for sample vessels: 96 deep-well plates or 6-well sample strips. For processing up to 16 samples, deep well plates are used. When processing 8 or fewer samples, the 6-well sample strips are ideal and are loaded onto the included aluminum rack. These sample strips reduce waste and lower consumable costs when processing fewer samples.

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